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Research Funding Impact

Since 1993, the AACR has awarded more than $542 million in grants to fund meritorious research projects across the spectrum of cancer science, including basic, translational, and clinical research. See how the AACR grants program has contributed to the AACR's mission.

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One-of-a-Kind Opportunity to Meet the Research Grant Reviewers at the AACR Annual Meeting 2026

One-of-a-Kind Opportunity to Meet the Research Grant Reviewers at the AACR Annual Meeting 2026

Attendees at the 2026 AACR Annual Meeting are invited to attend an interactive session on Monday, April 20, 2026, featuring AACR research grant reviewers Greg Delgoffe, PhD, and Rulla Tamimi, ScD. Meet the Research Grant Reviewers will offer attendees the opportunity to ask grant-related questions to seasoned reviewers. Continue reading to learn more about the event speakers and what to expect from this session.

Category: Grantee News
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Age: More than a Demographic in Breast Cancer 

Age: More than a Demographic in Breast Cancer 

Many people accept illness as an inevitable part of aging. But in breast cancer, the relationship between age and tumor biology is more complex than it may seem. Supported by one of the inaugural 2023 Victoria’s Secret Global Fund for Women’s Cancers Rising Innovator Grants, in Partnership with Pelotonia and AACR, Dr. Sandra McAllister is investigating how aging shapes breast cancer at the molecular level.

Category: Grantee Impact
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Armored for Victory: Reprogramming CAR T Cells Against Neuroblastoma

Armored for Victory: Reprogramming CAR T Cells Against Neuroblastoma

Transforming outcomes for children with high-risk cancers demands innovation. In 2023, Kristopher Bosse, MD, a physician-scientist at the Children’s Hospital of Philadelphia, received the AACR-AstraZeneca Career Development Award for Physician-Scientists, a grant designed to empower early-career investigators to bridge the gap between laboratory discoveries and clinical breakthroughs. His AACR-supported research, published in Molecular Therapy, explores promising new directions in immunotherapy for children with neuroblastoma.

Category: Grantee Impact
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RNA to the Rescue: A New DNA Repair Pathway for Double-Strand Breaks

RNA to the Rescue: A New DNA Repair Pathway for Double-Strand Breaks

2020 AACR Swim Across America Fellowship recipient Manisha Jalan, DPhil, reveals a novel DNA repair mechanism in human cells where RNA transcripts, once thought to be passive messengers, actively guide the repair of double-strand breaks. Mediated by the DNA polymerase ζ complex, this RNA-templated repair pathway introduces a new dimension to genome maintenance and challenges long-held biological dogma.

Category: Grantee Impact
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Cholesterol: A Fork in the Road for Pancreatic Cancer

Cholesterol: A Fork in the Road for Pancreatic Cancer

Pancreatic cancer outcomes can differ depending on where the disease metastasizes, with lung involvement generally associated with better prognosis than liver involvement. Supported by a 2022 AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grant, Rushika Perera, PhD and her team at UCSF uncovered a key insight: a protein player in cholesterol metabolism, PCSK9, predicts whether pancreatic cancer cells colonize the liver or lungs. This discovery provides new understanding of metastatic behavior and potential therapeutic strategies.

Category: Grantee Impact
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