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AACR-AstraZeneca/MedImmune Clinical Immuno-oncology Research Training Fellowships | Grant Status - Closed

Grant Amount$ 100,000 USD

Expected Number of
Funded Grants

2

Grant Term

1 Year(s)

Start of Grant Term

9/1/2018

Application Deadline

7/6/2018 1:00:00 PM

Application Deadline Time Zone

Eastern Standard Time

Decision Date

8/2018

Additional Information

April 2, 2019 – Grant recipient must attend the Grants Reception and Dinner to formally accept the grant. Grant funds may be used to support the grantees’ registration and attendance at this Annual Meeting.

Program Guidelines and Application Instructions are available in PDF format.

Description

Physician-scientists often receive world-class training in patient care, including the newest technologies and approaches to diagnose and treat disease.  However, these clinicians also require additional training in laboratory and clinic-based research, in order to stay up-to-date with the pace of medical progress.  As such, many fellowship programs offer a "research" year to these young physician-scientists to ensure they have sufficient expertise to contribute to laboratory-based research projects or clinical trials that will advance medical practice and improve patient outcomes.

Many of these training experiences occur in an academic setting, and are focused mainly on retrospective clinical trials, or basic, laboratory-based science; there is a paucity of training opportunities for clinical fellows to gain expertise in conducting an early-stage or a late-stage clinical trial.  The AACR-AstraZeneca/MedImmune Clinical Immuno-oncology Research Training Fellowships Program is designed to fill this knowledge gap by providing physician-scientists with real-world experience in early-stage or late-stage clinical development at the facilities of AstraZeneca and its Affiliates.

Each fellowship provides $100,000 over one year to support the salary and benefits of the fellow while working on a mentored research project at one of facilities of AstraZeneca and its Affiliates. Outstanding fellows may be invited to extend the fellowship for an additional year.

It is anticipated that two fellowships will be funded, one for early-stage research and one for late-stage clinical development in immuno-oncology research.

Program Guidelines

Program Guidelines and Application Instructions are available in PDF format.

Research Project Criteria

​During the research year at one of the facilities of AstraZeneca or one of its Affiliates, the fellows will be paired with an AstraZeneca scientist who will serve as their mentor. Research conducted during this year will provide the fellow with the opportunity to gain experience in drug development and understand challenges in early-stage and late-stage immuno-oncology (IO). The fellows will learn the fundamentals of conducting early-phase or late-phase clinical research in IO, such as understanding potential predictors of response to IO therapies, identifying early response endpoints, and developing optimal trial design methods for evaluating a large number of novel IO-IO and IO-Standard of Care combinations and quickly identifying the most promising combinations. They will also learn about trial design, data analysis, and protocol development during their fellowship. The fellows will be accountable for executing clinical research in IO and completing the research within the one-year program. Outstanding fellows may be invited to extend the fellowship for an additional year. Opportunities for publication and presentation of the research will be provided, including participation in the annual AstraZeneca Scientific Forum for Fellows.

Eligibility Criteria

Applicants must have a medical degree (including MD, DO, or MD/PhD) in a related field, and not currently be a candidate for a further doctoral degree. Additionally, at the start of the grant term, eligible applicants must have completed their most recent residency within the past 5 years and must be currently working at an academic, medical, or research institution within the United States.

Employees or subcontractors of a U.S. government entity or for-profit private industry are not eligible.

Any individual who currently holds an active AACR grant may not apply. Past grantees may apply if they complied with all progress and financial report requirements.

Investigators may submit only one application for the AACR-AstraZeneca/MedImmune Clinical Immuno-oncology Research Training Fellowships but may concurrently apply for other AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.

Citizenship Requirements

There are no citizenship requirements. However, by submitting an application for this grant, the applicant who is not a U.S. citizen or a permanent resident assures that the visa status will provide sufficient time to complete the project and grant term.

AACR Membership Requirements

​AACR membership is required. Nonmembers interested in this grant opportunity must submit a satisfactory application for AACR Associate Membership by Friday, July 6, 2018. Nonmembers can apply for membership using the Official Application for Membership submitted to the AACR with the required documents or apply online. In support of the professional development of early-career investigators, no annual dues are required for Associate membership.

Application Instructions

​AACR requires applicants to submit an electronic application by 1:00 p.m., U.S. Eastern Time on Friday, July 6, 2018, using the proposalCENTRAL website at https://proposalcentral.altum.com.