Specific Components of the Tumor Immune Microenvironment May Affect the Durability of Responses to BCMA CAR T-cell Therapy
Results suggest that immune cells beyond CAR-T cells impact the efficacy of CAR T-cell therapy PHILADELPHIA – Patients with...
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Benefits of Pre-surgical Immunotherapy Were Independent of Race in Patients with Aggressive Breast Cancer
Outcomes were similar between Black patients and patients of other races PHILADELPHIA – Treatment outcomes were similar between Black...
Eligible Younger Americans Less Likely to Meet Recommended Colorectal Cancer Screening Guidelines and Face Greater Disparities
Researchers caution that disparities may worsen as the recommended screening age is lowered PHILADELPHIA – In 2018, Americans aged...
Accuracy of Diagnostic Mammograms May Vary Across Racial and Ethnic Groups
PHILADELPHIA – The accuracy of diagnostic mammograms differed across racial and ethnic groups, with variation in several measures of...
Adolescent and Young Adult Leukemia Survivors Face Higher Mortality Rates Than the General Population for Decades After Diagnosis
Age, sex, and decade of diagnosis influenced long-term survival PHILADELPHIA – The long-term survival of adolescent and young adult...
Genomic Profiling of Pediatric Cancer May Expand Treatment Options for Patients Experiencing a Relapse
Patients were matched to therapies targeting specific mutations found in their cancers PHILADELPHIA – Genomic sequencing of tumors from...
T-cell Responses May Help Predict Protection Against SARS-CoV-2 Infection in Individuals With and Without Cancer
PHILADELPHIA – T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from...
Newly Characterized Mutation May Define Novel Pediatric AML Subtype
PHILADELPHIA – A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML)...
Rural Residents Tend to Hold Fatalistic Beliefs and Perceive More Cancer-related Information Overload Than Urban Residents
PHILADELPHIA – Compared to U.S. urban adults, rural adults were more likely to think fatalistically about cancer and feel...
Younger Individuals May Have the Highest Risk of Presenting with Distant-stage Colorectal Cancer
Risk may be greatest among young Black and Hispanic subgroups PHILADELPHIA – Individuals between 20 and 39 years old...