AACR Applauds Nomination of Stephen M. Hahn, MD, as FDA Commissioner
PHILADELPHIA — The American Association for Cancer Research (AACR), the world’s first and largest cancer research organization dedicated to...
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AACR Project GENIE Begins Five-year Collaborative Research Project with $36 Million in New Funding
The project will further enhance a unique, real-world clinico-genomic dataset through the joint efforts of nine biopharmaceutical companies PHILADELPHIA...
Award Winners Named for the 2019 San Antonio Breast Cancer Symposium
SAN ANTONIO — The San Antonio Breast Cancer Symposium (SABCS) and the American Association for Cancer Research (AACR), an...
Tipifarnib Shows Promising Clinical Activity in Patients With HRAS-mutant Head and Neck Cancer
BOSTON – The investigational farnesyl transferase inhibitor tipifarnib yielded durable objective responses in patients with recurrent and metastatic head...
MRTX849 Shows Clinical Activity in Patients With KRAS G12C-mutant Solid Cancers
BOSTON The investigational KRAS G12C inhibitor MRTX849 yielded clinical responses in patients with non-small cell lung cancer (NSCLC) and...
Selumetinib Shows Clinical Benefit in Adult Patients with Neurofibromatosis Type 1-Associated Plexiform Neurofibromas
BOSTON – The investigational MEK inhibitor selumetinib showed clinical responses in adult patients with neurofibromatosis type 1-associated plexiform neurofibromas,...
CDK4/6 Inhibitors Effective in Mice Bearing Multiple Human Cancer Types
BOSTON – Cyclin-dependent kinase (CDK) inhibitors, including palbociclib, were effective against patient-derived xenograft (PDX) mouse models of different tumor...
Bispecific Antibody MCLA-128 Shows Clinical Activity in Patients With Solid Tumors Harboring NRG1 Gene Fusions
BOSTON – The investigational bispecific HER2/HER3 antibody therapeutic MCLA-128 showed radiological and clinical responses in patients with metastatic pancreatic...
AG-270 is Safe and Shows Signs of Activity in Patients with Cancers Lacking the MTAP Gene
BOSTON – The investigational therapeutic AG-270, which targets the protein MAT2A, was safe, tolerable, and showed signs of activity...
AACR Congratulates Newest Members of the National Academy of Medicine
Among those recognized are 19 members of the AACR PHILADELPHIA – The American Association for Cancer Research (AACR) congratulates...