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AACR Grantees Present Their Work at the AACR Annual Meeting 2025 

The AACR Annual Meeting 2025 welcomes the global cancer community to the McCormick Place Convention Center in Chicago, April 25-30. Dozens of AACR grantees have been selected to present their work in oral and poster presentations, showcasing  the progress they have made with support from the AACR and its funding partners. 

Please explore the breadth of topics that will be covered over the six days of the conference. Follow the links below to learn more and add the sessions to individual itineraries. 

Sunday, April 27  

Aaron Hosios (left), with Dr. Matthew Vander Heiden (right)

OPENING PLENARY 

9:30-11:30 a.m., Hall GH, Ground Level, Convention Center
Matthew G. Vander Heiden, PhD, AACR Annual Meeting 2025 Program Committee Co-Chair, recipient of the 2014 AACR Gertrude B. Elion Cancer Research Award 

MINISYMPOSIUM 

The Stromal-Immune Interplay in Cancer Progression
4:35-4:50 p.m., Room S106, McCormick Place South (Level 1) 
Milos Spasic, PhD
, recipient of the 2023 AACR-AstraZeneca Breast Cancer Research Fellowship 

POSTER PRESENTATIONS 

Session: Gene Regulation and Transcription Factors 
Epigenetic dysregulation of IGF1 and PPARG2 in dedifferentiated liposarcoma 
Erica M. Pimenta, MDPhD, recipient of the 2024 AACR-QuadW Foundation Sarcoma Research Fellowship in Memory of Willie Tichenor 

Session: Genomic Diversity and Disparities in Cancer: Global Insights into Epidemiology, Risk, Outcomes and Precision Medicine 
Germline-somatic interactions in non-small cell lung cancer (NSCLC) patients from Latin America 
Javiera Garrido, PhD, recipient of the 2023 AACR Maximizing Opportunity for New Advancements in Research in Cancer (MONARCA) Grant for Latin America 

Monday, April 28  

MINISYMPOSIUM 

Metabolic Frontiers in Cancer: Amino Acids, Nutrient Dependencies, and Therapeutic Opportunities 
2:35-2:50 p.m., Room E450 B, McCormick Lakeside Center (Level 4) 
Christina Demetriadou, PhD, recipient of the 2024 AACR Anna D. Barker Basic Cancer Research Fellowship 

POSTER PRESENTATIONS 

Session: Cancer Disparities in Behavioral, Psychological, Psychosocial, and Molecular Factors 
Molecular epidemiology of high-risk HPV circulating in women living with HIV in Nigeria: protocol for a multi-center cross-sectional study 
Ijeoma M. Ifeorah, BMLS, MSc, PhD, recipient of the 2024 Beginning Investigator Grant for Catalytic Research (BIG Cat)

Session: Genome Maintenance: Mechanisms and Novel Therapeutics 
POLQ facilitates annealing mediated long deletions at chromosomal break in homologous recombination deficient cancers 
Manisha Jalan, DPhil, recipient of the 2020 AACR-Swim Across America Cancer Research Fellowship 

Session: Targeting the Tumor Microenvironment: A Brave New World 
An ex vivo culture platform of invasive lobular breast cancer for the screening of novel drugs targeting the tumor microenvironment
Julia M. Houthuijzen, PhD,recipient of the 2024 AACR-Lobular Breast Cancer Alliance-Deborah Mueller Foundation Fund Invasive Lobular Carcinoma Innovation and Discovery Grant

Session: Novel Drug Delivery Technologies 
Use of lipid nanoparticles to generate CAR T cells targeting colon cancer 
Pedro Pires Goulart Guimaraes, PhD, recipient of the 2024 AACR Maximizing Opportunity for New Advancements in Research in Cancer (MONARCA) Grant for Latin America 

Session: Novel Drug Resistance Mechanisms 
Fumarylacetoacetate hydrolase (FAH) stimulates resistance to CDK4/6 inhibitors in hormone receptor-positive breast cancer via a novel non-canonical function 
Jenny Hogstrom, PhD, recipient of the 2023AACR-AstraZeneca Breast Cancer Research Fellowship 

Tuesday, April 29  

AWARDS AND LECTURES 

AACR Gertrude B. Elion Cancer Research Award Lecture: Deconstructing benign-to-malignant transition in the colon 
12-12:30 p.m., Room S101, McCormick Place South (Level 1) 
Peter Maxwell Kienitz Westcott, PhD, recipient of the 2024 AACR Gertrude B. Elion Cancer Research Award 

FORUM 

Testing Diet with the Rigor of Drug: Dietary Interventions to Improve Cancer Treatment Outcomes 
5-6:30 p.m., Room 5, Upper Level, Convention Center 
Marcus DaSilva Goncalves, MD, PhD, recipient of the 2020 AACR-The Mark Foundation for Cancer Research “Science of the Patient” (SOP) Grant  

POSTER PRESENTATIONS 

Session: Development of Chemopreventive Agents and Preclinical Models 
Interactions between endocrine-targeting therapies and short-chain fatty acids in reducing ER+ breast cancer 
Alana A. Arnone, PhD, recipient of the 2024 AACR-AstraZeneca Breast Cancer Fellowship for Endocrine Therapy Research 

Session: Metabolic Reprogramming 
Metabolic shift towards the de novo serine pathway in non-transformed breast cells drives epigenetic plasticity, oxidative DNA damage, and pro-tumorigenic changes associated with aging 
Mariana Bustamante Eduardo, PhD, recipient of the 2023 AACR-Pfizer Breast Cancer Research Fellowship 

Session: Innate Immunity to Tumors 
Therapeutic benefits of innate immunity stimuli in hepatocellular carcinoma 
Longyue Lily Cao, MD, PhD, recipient of the 2024 AACR-Genentech Immuno-oncology Research Fellowship 

Session: The Tumor Immune Interplay as a Driver of Progression 
Targeting mTORC2 in lung squamous cell carcinoma improves anti-tumor immunity through the PSGL-1-VISTA axis 
Verra Ngwa, PhD, recipient of the 2024 AACR- Lung Cancer Initiative at Johnson & Johnson Stimulating Therapeutic Advances through Research Training (START) Grant 

Session: The Immune Microenvironment in Cancer 
The significance of CD200R1 on NK cells in the endometrial cancer tumor microenvironment 
Youssef Youssef, MD, recipient of the 2024 AACR-AstraZeneca Endometrial Cancer Research Fellowship 

Session: Proteomic Biomarkers and Therapeutics 
Covalent ligands that selectively disrupt CDK4-CDC37/HSP90 interactions in cancer cells 
Zachary E. Potter-Engelskirger, PhD, recipient of the 2024 AACR-AstraZeneca Breast Cancer Fellowship for Endocrine Therapy Research 

Wednesday, April 30  

PLENARY SESSION 

Opportunities in Predictive Oncology 
8-10 a.m., Arie Crown Theater, McCormick Lakeside Center (Level 2) 
Marleen Kok, MD, PhD, recipient of the 2023 Victoria’s Secret Global Fund for Women’s Cancers Rising Innovator Research Grant, in Partnership with Pelotonia & AACR 

MAJOR SYMPOSIUM 

Hubs of Anti-Tumor Immunity: Lymph Nodes and Lymphoid Structures 
10:15-11:45 a.m., Location to be announced
Amanda W. Lund, PhD, recipient of the 2022 AACR-Bristol Myers Squibb Midcareer Female Investigator Grant 

POSTER PRESENTATIONS 

Session: Late-Breaking Research: Tumor Biology
Capture the early benign-to-malignant transition of colon cancer in the mouse
Peter Maxwell Kienitz Westcott, PhD, recipient of the 2024 AACR Gertrude B. Elion Cancer Research Award 

Session: Mechanisms of Cancer Therapeutics 
Influence of glutathione S transferase T1 and M1 polymorphisms on tamoxifen metabolism in Malian women with breast cancer 
Brehima Diakite, MD, PhD, recipient of the 2023 Beginning Investigator Grant for Catalytic Research (BIG Cat) 

Session: Revolutionizing Cancer Care through Inclusive Clinical Research 
Understanding race-specific differences in the predictive performance of computational outcome models for breast cancer 
Francisco Sanchez-Vega, PhD, recipient of the 2024 Breast Cancer Research Foundation-AACR Career Development Awards to Promote Diversity and Inclusion