In This Section

Program

Please note that this meeting will take place as an in-person event in San Diego and will not live-stream content for virtual participation. The meeting content will be recorded and made available as an on-demand program after the conference.

All presentations are scheduled to be live, in-person presentations at the date and time specified below unless noted otherwise.  Program in progress.

Thursday, October 19, 2023

Friday, October 20, 2023

Saturday, October 21, 2023

Sunday, October 22, 2023

Thursday, October 19, 2023

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WELCOME AND OPENING KEYNOTE
6-7:15 P.M.

Welcome from Cochairs

Targeting PI3K for treating breast cancer
Lewis C. Cantley, Dana-Farber Cancer Institute, Boston, Massachusetts

OPENING RECEPTION
7:15-9 P.M.

Friday, October 20, 2023

CONTINENTAL BREAKFAST
7-8 A.M.
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PLENARY SESSION 1: models
8-10:15 A.M.

Breast cancer evolution
Joan S. Brugge, Harvard Medical School, Boston, Massachusetts

Patient-derived models of breast cancer for discovery science and precision medicine
Alana L. Welm, University of Utah Huntsman Cancer Institute, Salt Lake City, Utah

Title to be announced 
Jos Jonkers, Netherlands Cancer Institute, Amsterdam, Netherlands

Short talks from proffered abstracts

BREAK
10:15-10:30 A.M.
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PLENARY SESSION 2: Inflammation, the Microenvironment, and Metabolism
10:30 A.M.-12:45 P.M.

Title to be announced 
Robert Weinberg, MIT Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 

Title to be announced
Pepper Schedin, Oregon Health and Science University, Portland, Oregon

Highly multiplexed imaging for personalised breast immuno-oncology
H. Raza Ali, CRUK Cambridge Institute/University of Cambridge, Cambridge, United Kingdom

Short talks from proffered abstracts

LUNCH
12:45-2:30 P.M.
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PLENARY SESSION 3: Panel Discussion on Biomarkers
2:30-4:30 P.M.

Quantitative biomarkers for breast cancer patients
Charles M. Perou, University of North Carolina, Chapel Hill, North Carolina

Title to be announced
Gordon B. Mills, Oregon Health and Science University, Portland, Oregon

Optimal therapy outcome for high-risk breast cancer patients by response predictive subtypes
Laura J. van ‘t Veer, University of California San Francisco, San Francisco, California

Poster Session A/Reception
5-7 P.M.

Saturday, October 21, 2023

CONTINENTAL BREAKFAST
7-8 A.M.
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PLENARY SESSION 4: Functional interpretation of “Omics”
8-10:15 A.M.

Using a cancer dependency map
William C. Hahn, Dana-Farber Cancer Institute, Boston, Massachusetts

Title to be announced 
Christina Curtis, Stanford University, Stanford, California 

Additional speaker to be announced

Short talks from proffered abstracts

BREAK
10:15-10:30 A.M.
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PLENARY SESSION 5: Heterogeneity
SESSION CHAIR: Jane E. Visvader, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia
10:15 A.M.-12:15 P.M.

Decoding normal breast tissues and premalignant cancer with single cell genomics
Nicholas E. Navin, The University of Texas MD Anderson Cancer Center, Houston, Texas

Title to be announced 
Samuel Aparicio, BC Cancer Research Centre, Vancouver, BC, Canada 

Creation and preliminary analyses of a full spectrum of breast cancers initiated de novo from normal human mammary cells
Connie J. Eaves, BC Cancer Research Institute, Vancouver, BC, Canada 

Short talks from proffered abstracts

LUNCH ON OWN
12:45-2:45 P.M.
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PLENARY SESSION 6: personalized risk and prevention
2:45-5 P.M.

Harnessing endocrine control mechanism for breast cancer prevention 
Cathrin Briskin, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 

Genetic susceptibility to breast cancer: Recent advances and application to personalised prevention
Douglas Easton, University of Cambridge, Cambridge, United Kingdom

Title to be announced 
Susan M. Domchek, University of Pennsylvania, Philadelphia, Pennsylvania

Short talks from proffered abstracts

POSTER SESSION B / RECEPTION
5-7 P.M.

Sunday, October 22, 2023

CONTINENTAL BREAKFAST
7-8 A.M.
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PLENARY SESSION 7: mechanisms of treatment resistance
SESSION CHAIR: Jason S. Carroll, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom
8-10 A.M.

Redefining luminal breast cancer subtypes 
Wilbert Zwart, Netherlands Cancer Institute, Amsterdam, Netherlands 

Mechanisms of resistance to HER2 tragedy therapies
Rachel Schiff, Baylor College of Medicine, Houston, Texas

Title to be announced
Carlos L. Arteaga, UT Southwestern Medical Center, Dallas, Texas

Short talks from proffered abstracts

BREAK
10-10:20 A.M.
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PLENARY SESSION 8: future therapies and immuno-oncology
SESSION CHAIR: Pepper Schedin, Oregon Health and Science University, Portland, Oregon
10:20 A.M.-12:20 P.M.

Title to be announced  
Jenny C. Chang, Houston Methodist Hospital Cancer Center, Houston, Texas

Microbiota and breast cancer: the power of small things
Dipali Sharma, Johns Hopkins University School of Medicine, Baltimore, Maryland

Exploring breast cancer vulnerabilities through apoptotic pathways
Geoffrey J. Lindeman, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia

Short talks from proffered abstracts

CLOSING keynote
12:15-1 P.M.

Breast cancer: Enormous progress, ongoing challenges
Judy E. Garber, Dana-Farber Cancer Institute, Boston, Massachusetts

CLOSING Remarks
1 P.M.