Program
SUNDAY, NOVEMBER 17
Monday, NOVEMBER 18
- Plenary Session 1: Organ-Specific Microenvironments and Metastasis
- Plenary Session 2: Systemic Macroenvironment and Metastasis: Effects of Aging and Stress
- Plenary Session 3: The Metabolic Microenvironment, including Immune Metabolism
- Plenary Session 4: Metabolic Macroenvironment: Obesity and Cancer Cachexia
Tuesday, NOVEMBER 19
- Plenary Session 5: Stromal Changes as Tissue Becomes Tumor: The Expanding Functions of TME Components
- Plenary Session 6: Multicellular Interactions within Tumor Immune Microenvironments
- Plenary Session 7: Inflammation, the Immune Microenvironment, and the Systemic Interface
Wednesday, NOVEMBER 20
- Plenary Session 8: Microbiome and Immune Therapy
- Plenary Session 9: Therapy-induced Changes in Organ-specific Microenvironment and Therapeutic Strategies for Targeting the TME
- Closing Remarks
REGISTRATION
4-8 p.m.
Welcome and Introduction
5:30-6:15 p.m.
- Mikala Egeblad, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
- Neta Erez, Tel Aviv University, Tel Aviv, Israel
- Sergei Grivennikov, Cedars-Sinai Medical Center, Los Angeles, California
- Ilaria Malanchi, The Francis Crick Institute, London, England
Opening Keynote Address
6:15-7 p.m. | CME Eligible
- Introduction of keynote speaker
- Title to be announced
Ashani T. Weeraratna, John Hopkins University, Baltimore, Maryland
Continental Breakfast
7-8 a.m.
Plenary Session 1: Organ-Specific Microenvironments and Metastasis
8-10 a.m. | CME Eligible
- Understanding and overcoming the numbers game that underlies disseminated tumor cell immune evasion
Cyrus M. Ghajar, Fred Hutch Cancer Center, Seattle, Washington - Title to be announced
Ilaria Malanchi, The Francis Crick Institute, London, United Kingdom - Dissecting plasticity during colorectal cancer metastasis
Karuna Ganesh, Memorial Sloan-Kettering Cancer Center, New York, New York
Short talks from highly rated abstracts
Break
10-10:30 a.m.
Plenary Session 2: Systemic Macroenvironment and Metastasis: Effects of Aging and Stress
10:30 a.m.-12:30 p.m. | CME Eligible
- Title to be announced
Mikala Egeblad, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York - Understanding the immune macroenvironment to improve outcomes for older breast cancer patients
Sandra S. McAllister, Brigham and Women’s Hospital, Boston, MA - Respiratory virus infections promote metastatic outgrowth through alterations in immune landscapes
James V. DeGregori, University of Colorado Anschutz Medical Campus, Aurora, Colorado
Short talks from highly rated abstracts
Lunch on Own
12:30-2:30 p.m.
Plenary Session 3: The Metabolic Microenvironment, including Immune Metabolism
2:30-4:30 p.m. | CME Eligible
- Systemic and local metabolites controlling cancer immunity
Greg M. Delgoffe, University of Pittsburgh, Pittsburgh, Pennsylvania - Modulating amino acid cross talk between cancer and the host to improve diagnosis and therapy
Ayelet Erez, Weizman Institute of Science, Rehovot, Israel - Metabolic networks in the tumor microenvironment
Costas Lyssiotis, University of Michigan, Ann Arbor, Michigan
Short talks from highly rated abstracts
Break
4:30-5 p.m.
Plenary Session 4: Metabolic Macroenvironment: Obesity and Cancer Cachexia
5-7 p.m. | CME Eligible
- Intratumoral immune cells and their role in cancer cachexia
Marcus DaSilva Gonsalves, Weill Cornell Medicine, New York, New York - Lydia Lynch, Brigham and Women’s Hospital, Boston, Massachusetts
- Swarnali Acharya, Columbia University, New York, New York
Short talks from highly rated abstracts
Lightning Talks
7:30-9 p.m.
POSTER SESSION A AND RECEPTION
7-8:30 p.m.
Continental Breakfast
7-8 a.m.
Plenary Session 5: Stromal Changes as Tissue Becomes Tumor: The Expanding Functions of TME Components
8-10:15 a.m. | CME-Eligible
- Neta Erez, Tel Aviv University, Tel Aviv, Israel
- Edna Cukierman, Fox Chase Cancer Center, Philadelphia, Pennsylvania
- Kairbaan Hodivala-Dilke, Cancer Research UK, London, United Kingdom
- Vascular control of metastasis
Hellmut G. Augustin, Heidelberg University & German Cancer Research Center (DKFZ) Heidelberg, Germany
Short talks from highly rated abstracts
BREAK
10:15-10:45 a.m.
Plenary Session 6: Multicellular Interactions within Tumor Immune Microenvironments
10:45 a.m-12:45 p.m. | CME-Eligible
- Lisa Coussens, Oregon Health and Science University, Portland, Oregon
- Modulation of pancreatic tumor microenvironment and immune response
Yulia Pylaeva-Gupta, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina - Cedric Blanpain, Free University of Brussels, Brussels, Belgium
Short talks from highly rated abstracts
Lunch on own
12:45-2:30 p.m.
Plenary Session 7: Inflammation, the Immune Microenvironment, and the Systemic Interface
2:30-4:30 p.m. | CME-Eligible
- Title to be announced
Leah M. Cook, Nebraska Medical Center, Omaha, Nebraska - Microbes and cytokines regulating tumor microenvironment and metastasis
Sergei Grivennikov, Cedars-Sinai Medical Center, Los Angeles, California - Dissecting how breast tumours hijack myelopoiesis to promote metastasis
Karin E. de Visser, Netherlands Cancer Institute, Amsterdam, Netherlands
Short talks from highly rated abstracts
LIGHTNING TALKS
4:30-5 p.m.
POSTER SESSION B AND RECEPTION
4:30-6 p.m.
Continental Breakfast
7-8 a.m.
Plenary Session 8: Microbiome and Immune Therapy
8-10 a.m. | CME-Eligible
- Systemic and local metabolites controlling cancer immunity
Susan Bullman, Fred Hutch Cancer Center, Seattle, Washington - Florencia McAllister, University of Texas MD Anderson Cancer Center, Houston, Texas
- Giorgio Trinchieri, National Institute of Health, Bethesda, Maryland
Short talks from highly rated abstracts
BREAK
10-10:30 a.m.
Plenary Session 9: Therapy-induced Changes in Organ-specific Microenvironment and Therapeutic Strategies for Targeting the TME
10:30 a.m-12:30 p.m. | CME-Eligible
- Title to be announced
Adrienne Boire, Memorial Sloan Kettering Cancer Center, New York, New York - Age-related stromal changes drive tumorigenesis
Sheila A. Stewart, Washington University School of Medicine, St. Louis, Missouri - Implicit order, disease, and cancer
Garry P. Nolan, Stanford University School of Medicine, Stanford, California
Short talks from highly rated abstracts
CLOSING REMARKS
12:30 p.m.