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AACR Special Conference: Rethinking DCIS: An Opportunity for Prevention?

September 8-11, 2022
Sheraton Philadelphia Downtown
Philadelphia, Pennsylvania

Conference Cochairs:

Lisa M. Coussens, OHSU Knight Cancer Institute, Portland, Oregon
Laura J. Esserman, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
Kornelia Polyak, Dana-Farber Cancer Institute, Boston, Massachusetts
Jorge S. Reis-Filho, Memorial Sloan Kettering Cancer Center, New York, New York

Please note that this meeting will take place as an in-person event in Philadelphia and will not live-stream content for virtual participation. The meeting content will be captured and made available as an on-demand program after the meting. Please see the Registration page for details.

Ductal carcinoma in situ (DCIS) is a proliferation of abnormal, but noninvasive, cells within the ductolobular system of the breast. DCIS is often considered stage 0 breast cancer and accounts for one in five newly diagnosed breast cancers in the US. Without treatment approximately 14-50% of DCIS will advance to invasive cancer. This large variation in disease progression underscores the need for better understanding of DCIS. Identification of DCIS subpopulations with malignant potential may also be reflective of the various forms of more advanced breast cancers and offers a unique opportunity to understand the complex ecosystem of breast cancer. This conference will utilize an interdisciplinary approach to explore the latest advances in the detection, biological understanding, risk assessment, and treatment of DCIS.   

Original Artwork Description

Eve: The Constellations Within (A Cellular Tapestry) by Michael Endicott is an artistic salute to the scientific process pursued by physicians and medical researchers in their quest to deliver personalized treatment to their patients. Medicine is now capable of interpreting the universe within, from the macro to the micro, to weave treatments to fit our unique, individual, cellular constellations. Ductal Carcinoma in Situ (DCIS) is complex with potential to progress or regress. Advances in research and clinical trials are improving our predictive capabilities, bringing new and better treatment approaches.

This composite photograph is inspired by immune multiplex images segmenting the DCIS cells as seen in the research of Dr. Michael Campbell and Dr. Laura Esserman. Whether you look out to the farthest stars, or into the core of our cells, there is an infinity of creation and discovery. Eve is a composite of two photographs. One is a cellular constellation guiding us to better personalize treatment. The other is the woman, reminding us that it is the health and wellbeing of the patient that motivates our science.

Michael Endicott is a Fine Art Photographer in the San Francisco Bay Area whose photosculptures are designed to connect the micro and macro structures that give shape and life to our world. Follow his artistic process on IG @michaelbendicott or visit his web site at

Continuing Medical Education Activity AMA PRA Category 1 CreditsTM available