In This Section

The Evolving Tumor Microenvironment in Cancer Progression: Mechanisms and Emerging Therapeutic Opportunities


In association with the AACR Tumor Microenvironment (TME) working group

Abstract Submission DeadlineMonday, October 5, 2020, 11:59 ET
Advance Registration DeadlineThursday, November 19, 2020, 11:59 ET


January 9-12, 2021
Hilton Orlando Lake Buena Vista
Lake Buena Vista, Florida


Conference Cochairs

Yibin Kang, Princeton University, Princeton, New Jersey
Sheila A. Stewart, Washington University School of Medicine, St. Louis, Missouri
Valerie M. Weaver, University of California San Francisco, San Francisco, California

The complexity and functional contribution of the tumor microenvironment in cancer progression continues to expand at the cellular, organ and systemic level.  This complexity is observed within mesenchymal cells, cells of the immune system, metabolism as a form of communication, the roles mechanical communication and organ specification play in tumor progression, aging and obesity as microenvironmental factors at the tissue and systemic levels, and the microbiota.  It has been appreciated for some time that the tumor microenvironment plays a significant role in disease progression, response to therapy, invasion and metastasis or conversely, restraint of growth, but the precise function of each constituent remains mysterious.  The Conference Cochairs developed a program that will bring together experts from diverse fields to explore this intricacy.  The conference will provide an up-to-date overview of the recent advances in tumor microenvironment research at the basic, translational and clinical application levels.  Significant focus will be placed on developing areas of the tumor microenvironment and exploring platforms that provide junior investigators time to present their work and interact with senior investigators.