Close
FINDING CURES TOGETHER<sup>SM</sup>

AACR Annual Meeting 2015

NextGen Stars  

The NextGen Stars program provides an exciting opportunity to increase the visibility of early-career scientists at the AACR Annual Meeting and to support the professional development and advancement of those selected to speak.  Eight outstanding NextGen Stars will present their work in major sessions at the AACR Annual Meeting 2015.  Selections were made through a competitive application process that was limited to AACR Associate Members and AACR Active Members who were at the junior faculty level (not higher than assistant professor or equivalent). 

Congratulations to the 2015 NextGen Stars!

Christopher E. Barbieri, Weill Cornell Medical College of Cornell University, New York, New York
SPOP mutation is associated with genomic instability in prostate cancer
Recent Advances in Diagnostics and Therapeutics Research
Exploiting DNA Repair Deficiencies in Cancer

Monday, April 20, 2015, 10:30 a.m.-12:30 p.m.
Room 113, Pennsylvania Convention Center

Katherine B. Chiappinelli, Johns Hopkins School of Medicine, Baltimore, Maryland
Immunomodulatory and tumor cell killing effects of the demethylating agent 5-azacytidine in ovarian cancer
Major Symposium
Epigenetic Mechanisms in Cancer Risk

Wednesday, April 22, 2015, 10 a.m. - 12 p.m.
Room 120, Pennsylvania Convention Center

Ryan B. Corcoran, Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Clinical acquired resistance to RAF inhibitor combinations in BRAF mutant colorectal cancer through MAPK pathway alterations
Major Symposium
Mechanisms of Resistance: From Signaling Pathways to Stem Cells

Tuesday, April 21, 2015, 10 a.m. - 12 p.m.
Terrace Ballroom II-III (400 Level), Pennsylvania Convention Center

Courtney Hodges, Howard Hughes Medical Institute and Stanford University School of Medicine, Stanford, California
Chromatin accessibility underlies the tumor-suppression role of BAF (mSWI/SNF) complexes in many malignancies
Recent Advances in Diagnostics and Therapeutics Research
DNA Repair Pathways in Cancer: Basic Biology and Clinical Utility

Tuesday, April 21, 2015, 1 - 3 p.m.
Room 121, Pennsylvania Convention Center

Hongbo Pang, Sanford-Burnham Medical Research Institute, La Jolla, California
A novel endocytic and intercellular transport pathway for drug delivery across blood vessels and into nutrient-deprived tumor cells
Recent Advances in Diagnostics and Therapeutics Research
Novel Delivery Systems and/or Formulations in Cancer Treatment

Monday, April 20, 2015, 1 - 3 p.m.
Room 126, Pennsylvania Convention Center

Rushika M. Perera, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts
Transcriptional mechanisms for autophagy regulation and metabolic reprogramming in pancreatic cancer
Recent Advances in Organ Site Research
Pancreatic Cancer in 2015: An Integrated View of a Complex Disease

Wednesday, April 22, 2015, 10 a.m. - 12 p.m.
Room 118, Pennsylvania Convention Center

Catherine C. Smith, University of California, San Francisco, California
Polyclonal and heterogeneous resistance to targeted therapy in leukemia
Major Symposium
Targeted Therapies in Hematologic Malignancies

Monday, April 20, 2015, 10:30 a.m. -12:30 p.m.
Room 201, Pennsylvania Convention Center

Surojit Sur, Ludwig Center at the Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland
The Trojan Horse Strategy: Packaging chemotherapeutics can help alleviate toxicity
Major Symposium
Applying Systems Biology in the Oncology Clinic

Tuesday, Apr 21, 2015, 1 - 3 p.m.
Room 118, Pennsylvania Convention Center

Top of page

View the webcasts of the NextGen Stars' presentations from the AACR Annual Meeting 2014:

Andrea Bertotti, University of Turin, Turin, Italy
Rational drug combinations to improve anti-EGFR targeted therapies in metastatic colorectal cancer
Presented in a Current Concepts session on Novel Approaches for Understanding the Biology of Colorectal Cancer

Priscilla K. Brastianos, Massachusetts General Hospital, Boston, Massachusetts
Genomic characterization of 101 brain metastases and paired primary tumors reveals patterns of clonal evolution and selection of driver mutations (audio only)
Presented in a Major Symposium on Novel Mechanisms of Metastasis

Brooke M. Emerling, Weill Cornell Medical College, New York, New York
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53 null tumors
Presented in a Major Symposium on Synthetic Lethality

Maurizio Scaltriti, Memorial Sloan Kettering Cancer Center, New York, New York
Blockade of EGFR and HER3 enhances PI3K/Akt antitumor activity in triple negative breast cancer
Presented in a Current Concepts session on Breast Cancer: Progress in Basic and Translational Research

David T. Ting, Massachusetts General Hospital, Charlestown, Massachusetts
Diversity of circulating tumor cells in a mouse pancreatic cancer model identified by single cell RNA sequencing
Presented in a Current Concepts session on Single Cell Analysis of the Tumor

Top of page