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FINDING CURES TOGETHER<sup>SM</sup>

Tenth AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved

Monday, September 25 

Tuesday, September 26

Wednesday, September 27

Thursday, September 28


Monday, September 25 

Welcome and Opening Session
5:00 p.m.-7:00​ p.m.

Physical and social engagement: The anticancer effect
AACR President - Michael A. Caligiuri
, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio


Cancer Disparities Research: 10 Years ​of Progress and Promise​ ​Highlights of the most significant progress over the last 10 years, current challenges, and opportunities.

Colorectal Cancer
John M. Carethers, University of Michigan, Ann Arbor, Michigan

Breast cancer disparities: Progress, challenges, and opportunities
Christopher I. Li, Fred Hutchinson Cancer Research Center, Seattle, Washington

Prostate Cancer
Rick A. Kittles, City of Hope Comprehensive Cancer Center, Duarte, California

Research addressing cervical cancer disparities: Progress, challenges, and opportunities
Electra D. Paskett, Ohio State University Comprehensive Cancer Center, Columbus, Ohio


Eighth Annual AACR Distinguished Lectureship on the Science of Cancer Health Disparities, funded by Susan G. Komen®: Reducing racial disparities in breast cancer mortality: Modifiable etiologic factors, risk prediction, and outcomes
Julie R. Palmer, Boston University School of Public Health, Boston, Massachusetts


MICR Council Meet and Greet
7:00 p.m.-8:00 p.m.


Poster Session A / Opening Reception
8:00 p.m.-10:00 p.m.


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Tuesday, September 26 

Continental Breakfast / Professional Networking Roundtables
7:00 a.m.-8:00 a.m.


Plenary Session 1: Inflammation, Microbiome, and Cancer Disparities 
Session Chairs: Johanna W. Lampe, Fred Hutchinson Cancer Research Center, Seattle, Washington, and Stephen O’Keefe, University of Pittsburgh, Pittsburgh, Pennsylvania
8:00 a.m.-9:30 a.m.

Changes in the composition and activity of the colonic microbiome that may explain the extreme risk of colon cancer in Alaskan Native People
Stephen O’Keefe

Gut microbiome across racial/ethnic groups and associations with biomarkers of cancer risk
Johanna W. Lampe

Are changes in the esophageal microbiome responsible for the high squamous cell cancer health disparities in rural South Africans?
Vikash Sewram, African Cancer Institute, Stellenbosch University, South Africa


Break
9:30 a.m.-10:00 a.m.


Plenary Session 2: Forum and Town Hall – Strategic Opportunities for Cancer Health Disparities Research
Moderator: Rick A. Kittles, University of Arizona Cancer Center, Tucson, Arizona
10:00 a.m.-11:30 a.m.

Panelists:

William J. Blot, Vanderbilt University Medical Center, Nashville, Tennessee
Brian A. King, Center for Disease Control and Prevention, Atlanta, Georgia
Electra D. Paskett, Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Eliseo J. Pérez-Stable, National Institute on Minority Health and Health Disparities, Bethesda, Maryland
Sanya A. Springfield, National Cancer Institute, Bethesda, Maryland

Concurrent Sessions 1 & 2
11:30 a.m.-12:30 p.m.

Concurrent Session 1: Disparities in Pediatric Cancers
Session Chair: Michael E. Scheurer, Baylor College of Medicine, Dan L. Duncan Cancer Center, Houston, Texas

Childhood cancer disparities: Past, present, and future
Michael E. Scheurer

Poverty and pediatric leukemia outcomes
Kira Bona, Dana-Farber and Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts

The Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Study: A cohort profile
Philip J. Lupo, Baylor College of Medicine, Houston, Texas


Concurrent Session 2: Multi-Level Social Determinants of Cancer Health Disparities 
Session Chairs: Scarlett Lin Gomez, Cancer Prevention Institute of California, Fremont, California; Beti Thompson, Fred Hutchinson Cancer Research Center, Seattle, Washington; and Celette S. Skinner, UT Southwestern Medical Center, Dallas, Texas

Understanding cancer disparities in mortality and survivorship and social and built environments
Salma Shariff-Marco, Cancer Prevention Institute of California, Fremont, California

Not the same everywhere: The moderating role of context on cancer disparities
Sandi L. Pruitt, UT Southwestern Medical Center, Dallas, Texas

Neighborhood factors and changes in mammography screening rates in response to promotora intervention in Latinas
Shirley A. A. Beresford, University of Washington, Seattle, Washington


MICR Professional Advancement Session
12:30 p.m.-2:00 p.m.


Lunch on Own (for those not attending PAS)
12:30 p.m.-2:00 p.m.


Hot Topics in Cancer Health Disparities 1 
Session Chair: Laura Fejerman, University of California, San Francisco, California
2:00 p.m.-3:30 p.m.

Distinct genomic alterations in prostate cancer of African American men
Albert Dobi, Center for Prostate Disease Research (CPDR), Rockville, Maryland

β-catenin overexpression underlies the aggressive disease course in African American triple negative breast cancer patients that lack androgen receptor
Karuna Mittal, Georgia State University, Atlanta, Georgia

Somatic mutations and ancestry markers in Hispanic lung cancer patients
William D. Cress, Moffitt Cancer Center, Tampa, Florida

Development of a novel therapeutic splice-switching oligonucleotide targeting race-related androgen receptor signaling and aggressive prostate cancer
Jennifer A. Freedman, Duke University Medical Center, Durham, North Carolina

Estrogenic activity is associated with race/ethnicity and Indigenous American ancestry among San Francisco Bay Area women
Sylvia S. Sanchez, University of California, Berkeley, Berkeley, California

Differences in tumor infiltrating lymphocytes between racially-distinct triple negative breast tumors
Nikita Wright, Georgia State University, Atlanta, Georgia

 


Educational Sessions 1 & 2

3:30 p.m.-4:30 p.m.

Educational Session 1: Global Health and Environmental Exposures 
Session Chairs: John D. Groopman, Johns Hopkins University School of Public Health, Baltimore, Maryland, and Robert Hiatt, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Identifying an epigenetic basis for arsenic-associated bladder cancer in a population in Chihuahua, Mexico
Rebecca Fry, UNC Gillings School of Global Public Health, Chapel Hill, North Carolina

Title to be announced
Lourdes Baezconde-Garbanati, USC Keck School of Medicine, Los Angeles, California

Liver cancer among minority populations in the United States
Katherine A. McGlynn, National Cancer Institute, Rockville, Maryland


Educational Session 2: New Biological Models to Advance Cancer Health Disparities Research 
Session Chairs: John D. Carpten, USC Keck School of Medicine, Los Angeles, California, and Tiffany Wallace, National Cancer Institute, Rockville, Maryland    

Introduction
John D. Carpten and Tiffany Wallace

Cancer chemotherapy and the tools needed to advance treatment in a medical diverse population
Jennie L. Williams, Stony Brook University, Stony Brook, New York

Understanding the biology of TNBC and breast cancer stem cells in patients of diverse ethnicities
Evelyn M. Jiagge, University of Michigan Health System, Ann Arbor, Michigan

NCI's Patient-Derived Models Repository: Generating models from racial and ethnic minorities
Yvonne A. Evrard, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland


Poster Session B / Reception
4:30 p.m.-6:30 p.m.


Evening Off / Dinner on Own
6:30 p.m.-


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Wednesday, September 27 

Continental Breakfast / Professional Networking Roundtables
7:00 a.m.-8:00 a.m.


Plenary Session 3: Financial and Economic Burden of Cancer Survivorship
Session Chair: Edith P. Mitchell, Thomas Jefferson University Kimmel Cancer Center, Philadelphia, Pennsylvania, and K. Robin Yabroff, U.S. Department of Health and Human Services, Washington, D.C.
8:00 a.m.-9:30 a.m.

Financial well-being and health: Definitions and measurement issues
Reginald D. Tucker-Seeley, University of Southern California, Los Angeles, California

Physical challenges and their financial impact on survivors
Crystal S. Denlinger, Fox Chase Cancer Center, Philadelphia, Pennsylvania

Title to be announced
Alan Balch, Patient Advocate Foundation, Hampton, Virginia


Break
9:30 a.m.-10:00 a.m.


Plenary Session 4: Forum and Town Hall – Cancer Health Care for Underserved Patients in 2017 and Beyond 
Moderator: John M. Carethers, University of Michigan, Ann Arbor, Michigan​
10:00 a.m.-11:30 a.m.

Impact of Affordable Care Act on reducing cancer health disparities for the medically underserved
Timothy D. McBride, Washington University in St. Louis, Missouri

Health literacy and accessing equitable cancer health care
Mary Jackson Scroggins, In My Sister's Care and Pinkie Hugs, Washington, D.C.

Community-engaged cancer care: Connecting workforce, workplace, and clients
Maureen Y. Lichtveld, Tulane University, New Orleans, Louisiana

Disparities in lung cancer screening utilization: Effective outreach to the community
Christopher S. Lathan, Dana-Farber Cancer Institute, Boston, Massachusetts


Concurrent Sessions 3 & 4
11:30 a.m.-12:30 p.m.    

Concurrent Session 3: Disparities in Survivorship and Patient Outcomes 
Session Chairs: Leslie L. Robison, St. Jude Children's Research Hospital, Memphis, Tennessee, and Stephanie B. Wheeler, University of North Carolina at Chapel Hill, North Carolina

Disparities in survivors of pediatric, adolescent, and young adult cancers
Smita Bhatia, University of Alabama at Birmingham, Alabama

Developing effective community and health system partnerships to advance health equity and health disparities research
Nadine J. Barrett, Duke Cancer Institute, Durham, North Carolina

Disparities in breast cancer survivorship and outcomes
Lawrence Kushi, Kaiser Permanente, Oakland, California


Concurrent Session 4: Cancer in Rural Areas 

Session Chairs: Mark B. Dignan, University of Kentucky Markey Cancer Center, Lexington, Kentucky, and Kathryn E. Weaver, Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina

Rural disparities in uptake of well visits and access to cancer screening in Medicare under the Affordable Care Act
Roger T. Anderson, University of Virginia, Charlottesville, Virginia

Overcoming barriers to screening in rural areas: No bus, no taxi, no services
Beti Thompson, Fred Hutchinson Cancer Research Center, Seattle, Washington

A lay navigation program for older cancer survivors
Maria Pisu, University of Alabama at Birmingham, Alabama


Poster Session C / Lunch
12:30 p.m.-2:30 p.m.


Hot Topics in Cancer Health Disparities 2 
Session Chair: Jun J. Yang, St. Jude Children's Research Hospital, Memphis, Tennessee
2:30 p.m.-4:00 p.m.

Primary care utilization, late-stage diagnosis and timeliness of treatment among Medicaid cancer patients: Early signals following the ACA expansion
Jennifer Tsui, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Tumor masking or tumor aggressiveness? : A structural equations modeling approach to estimate the impact of breast density on breast cancer stage, overall and by race
Katherine Y. Tossas-Milligan, University of Illinois at Chicago, Chicago, Illinois

Patterns of bladder cancer incidence, tumor characteristics, and survival among Latinos in California: Results from the California Cancer Registry
Sumeet Syan-Bhanvadia, University of Southern California, Los Angeles, California

Factors associated with decreased survival in epithelial ovarian cancer patients from the southern United States
Sherri L. Stewart, Centers for Disease Control and Prevention, Atlanta, Georgia

Temporal patterns of breast cancer treatment initiation and completion among black and white women in the Carolina Breast Cancer Study
Sophie E. Mayer, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Considering unintended effects of a colorectal cancer navigation program in a federally qualified health center in Chicago on mammography uptake
Yazmin San Miguel, University of California San Diego, La Jolla, California


Educational Sessions 3 & 4
4:00 p.m.-5:00 p.m.

Educational Session 3: Forming Successful Collaborations and Building a Research Program 
Session Chairs: Sora Tanjasiri, Health Promotion Research Institute California State University, Fullerton, California, and Jeffrey N. Weitzel, City of Hope, Duarte, California

Not showing up empty-handed: A multi-community collaboration for cancer prevention and control
Sora Tanjasiri

Building and sustaining partnerships in cancer health disparities research
Chanita Hughes-Halbert, Medical University of South Carolina Hollings Cancer Center, Charleston, South Carolina

Providing a helping hand and appealing to the inner academic among community-based clinicians:  The Clinical Cancer Genomics Community Research Network
Jeffrey N. Weitzel

Successful collaboration: A community advocate’s perspective
Nia Aitaoto, University of Arkansas for Medical Sciences, Little Rock, Arkansas

Educational Session 4: Structural and Social Determinants of Cancer Disparities 
Session Chair: Eliseo J. Pérez-Stable, National Institute on Minority Health and Health Disparities, Bethesda, Maryland

Structural and social determinants of cancer disparities
Eliseo J. Pérez-Stable

Intersectional approaches to studying the interaction of multiple and multilevel social determinants on cancer health disparities
Scarlett Lin Gomez, Cancer Prevention Institute of California, Fremont, California

Structural interventions to reduce cancer disparities
Arleen Brown, UCLA General Internal Medicine and Health Services Research, Los Angeles, California


Evening Off / Dinner on Own
5:00 p.m.-


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Thursday, September 28 

Continental Breakfast / Professional Networking Roundtables
7:00 a.m.-8:00 a.m.


Plenary Session 5: Continental Obesity, the Obesity Paradox, and Cancer Disparities 
Session Chairs: Esther M. John, Cancer Prevention Institute of California, Fremont, California, and Bette Caan, Kaiser Permanente, Oakland, California
8:00-9:30 a.m.  

Explaining the obesity paradox in cancer: The role of muscle
Bette Caan

Obesity in breast and ovarian cancers: Racial / ethnic disparities
Elisa V. Bandera, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Racial / ethnic disparities in breast cancer risk associated with body size
Esther M. John

Multiethnic differences in BMI, body composition, and survival in colorectal and breast cancer
Elizabeth M. Cespedes Feliciano, Kaiser Permanente Division of Research, Oakland, California


Break
9:30 a.m.-9:45 a.m.


Plenary Session 6: Environmental Exposures and Cancer Health Disparities in Underserved Communities 
Session Chair: Johnnye Lewis, University of New Mexico Health Sciences Center, Albuquerque, New Mexico
9:45-11:15 a.m.

Disparate exposures of Native Americans to metal mixtures in abandoned mine waste in the west: Implications for cancer risk
Johnnye Lewis, University of New Mexico Health Disparities Center, Albuquerque, New Mexico

Diet, exposure and stem cells: Interactive determinants of mammary cancer risk and outcome
Robin S. Fuchs-Young, Texas A&M University Health Science Center, College Station, Texas

The role of intergenerational community cohorts to examine the burden of cancer from environmental exposures
Mary Beth Terry, Columbia University School of Public Health, New York, New York

Title to be announced
Edith Hood, Red Water Pond Community Association, Church Rock, New Mexico


Plenary Session 7: Vision for the Next 10 Years of Cancer Disparities Research 
11:15 a.m.-12:45 p.m.    

Clinical Research
Olufunmilayo I. Olopade, University of Chicago Medical Center, Chicago, Illinois

Population Sciences
Victoria L. Seewaldt, City of Hope, Duarte, California

Basic Research
John D. Carpten, USC Keck School of Medicine, Los Angeles, California

Multilevel Approaches
Timothy R. Rebbeck, Harvard School of Public Health, Boston, Massachusetts


Closing Remarks
12:45 p.m. 


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