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FINDING CURES TOGETHER<sup>SM</sup>

Molecular Biology in Clinical Oncology Workshop

​Program* 

*as of July 17, 2018

Sunday, July 22

Registration
2-5:30 p.m.


Welcome and Workshop Overview

5:30-6 p.m.

Mark W. Geraci, Indiana University, Indianapolis, Indiana


Workshop Pre-Test

6-6:30 p.m.


Welcome and Introduction of Keynote Lecture

6:30-6:35 p.m.

Ross L. Levine, Memorial Sloan Kettering Cancer Center, New York, New York

Keynote Lecture
Preclinical Cancer Target Validation: How Not to Be Wrong
William G. Kaelin, Jr., Dana-Farber Cancer Institute, Boston, Massachusetts


Opening Dinner and Reception

7:30-9:30 p.m.


Monday, July 23

Breakfast
7-8 a.m.


Grant Writing Tutorial

8-9 a.m.

William G. Kaelin, Jr., Dana-Farber Cancer Institute, Boston, Massachusetts


Lecture: Oral Presentations that Audiences Remember

9-9:50 a.m.

Michael A. Caligiuri, City of Hope, Duarte, California


Break

9:50-10:10 a.m.


Lecture:
Lineage Plasticity in Prostate Cancer
10:10-11 a.m.

Charles L. Sawyers, Memorial Sloan Kettering Cancer Center, New York, New York


Lecture:
Chromatin, Epigenetics, and Cancer
11-11:50 a.m.

Charles W.M. Roberts, St. Jude's Children's Research Hospital, Memphis, Tennessee


Faculty "Office Hours"

11:50 a.m.-1 p.m.
Sign-up will be available.


Lunch

1-2 p.m.


MBCO Class of 2018 Group Photograph

2-2:15 p.m.


Introduction to Laboratory Sessions^

2:25-2:45 p.m.

Laboratory Session Rotation #1^
2:45-5:45 p.m.

Laboratory 1: miRNA Research Using qPCR Technology
Camilla Heinzmann, Heinzmann Coaching and Consulting, Inc., Valencia, California
Maggie Soares, Heinzmann Coaching and Consulting, Inc., Toronto, Ontario, Canada
Amy Smith, QIAGEN, Inc., Germantown, Maryland

Laboratory 2: System-wide Cancer Characterization: From Protein Purification to Metabolic Flux
Nicholas A. Graham, University of Southern California, Los Angeles, California
Parag Mallick, Stanford University, Stanford, California
Nick Hartel, University of Southern California, Los Angeles, California

Laboratory 3: Next-Generation Sequencing: An Introduction and Applications for Oncology
Amanda Gedman, Illumina, Inc., Raleigh, North Carolina
Margaret Porter, Illumina, Inc., San Diego, California

Laboratory 4: RNA-seq Analysis in Cancer Biomarker Discovery and Network Interpretation
Michael G. Edwards, Bioinfo Solutions, Parker, Colorado
Tzu Phang, University of Colorado Anschutz Medical Campus, Aurora, Colorado
Robert Stearman, Indiana University School of Medicine, Indianapolis, Indiana

Laboratory 5: CRISPR/Cas9: The Genome Editing Revolution
Leigh Brody, Desktop Genetics, London, United Kingdom


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Tuesday, July 24

Breakfast
7-8 a.m.


Lecture:
Cell-Based Adoptive Immunotherapy – CAR T and More
8-8:50 a.m.

Carl H. June, Abramson Cancer Center of University of the Pennsylvania, Philadelphia, Pennsylvania


Lecture: Immunotherapy for Genitourinary Cancers – Laboratory and Clinical Perspectives

8:50-9:40 a.m.

Charles G. Drake, Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York


Break

9:40-10 a.m.


Lecture:
Understanding Responses To Cancer Therapy – The Tissue Is the Issue, but the Scoop Is in the Poop
10-10:50 a.m.

Jennifer A. Wargo, The University of Texas MD Anderson Cancer Center, Houston, Texas


Lecture:
Hitting the Target in Clinical Trials
10:50-11:40 a.m.

Jean Y. Tang, Stanford University School of Medicine, Redwood City, California


Lunch

12-1 p.m.


Grant Group Discussion #2

1-2:30 p.m.


Laboratory Session Rotation #2^

2:30-5:30 p.m.


Barbecue Dinner

6:30-8 p.m.


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Wednesday, July 25

Breakfast
7-8 a.m.


Laboratory Session Rotation #3^

8-11 a.m.


Lecture:
Resistance to Molecularly Targeted Therapies – Perspectives from the Dark Side
11:10 a.m.-12 p.m.

Jeffrey A. Engelman, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts


Lunch

12:15-1:15 p.m.


Grant Group Discussion #3

1:15-2:45 p.m.


Lecture:
Signaling and Epigenetics in Leukemia – A Sideways Journey 
2:45-3:35 p.m.

Ross L. Levine, Memorial Sloan Kettering Cancer Center, New York, New York


Lecture:
Systematic Approaches to Identify and Credential Cancer Targets
3:35-4:25 p.m.

William C. Hahn, Dana-Farber Cancer Institute, Boston, Massachusetts


Break

4:25-4:40 p.m.


Lecture:
Translational Genomics in an Age of Precision Oncology
4:40-5:30 p.m.

Barry S. Taylor, Memorial Sloan Kettering Cancer Center, New York, New York


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Thursday, July 26

Free Day
(No lectures or laboratory sessions)


Friday, July 27

Breakfast
7-8 a.m.


Laboratory Session Rotation #4^

8-11 a.m.


Grant Group Discussion #4

11 a.m.-12:30 p.m.


Trainees: Lunch on Own / Free Time
Faculty: Faculty Meeting and Lunch

12:30-2 p.m.


Faculty "Office Hours"

2-3 p.m.


Lecture:
There and Back Again – One Journey from Bench to Bedside to Industry
3-3:30 p.m.

Amanda J. Redig, Takeda Oncology, Cambridge, Massachusetts


Lecture: The Best of Both Worlds – Structure, Function, and Therapeutic Targeting of the EGF Receptor

4:40-5:30 p.m.

Christine M. Lovly, Vanderbilt University Medical Center, Nashville, Tennessee


Break

4:20-4:40 p.m.


Lecture: Responsible Conduct of Research

4:40-5:25 p.m.

Mark W. Geraci, Indiana University, Indianapolis, Indiana


Career Development Panel

5:30-6:30 p.m.


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Saturday, July 28

Breakfast
7-8 a.m.


Laboratory Session Rotation #5^

8-11 a.m.


Lecture:
Using Mouse Models to Study Sarcoma and Radiation Biology
11:10 a.m.-12 p.m.
David G. Kirsch, Duke University Medical Center, Durham, North Carolina


Lecture:
Lung Cancer Chemoprevention – Implications for Early Carcinogenesis
12-12:50 p.m.
Mark W. Geraci, Indiana University, Indianapolis, Indiana


Free Time / Working Lunch on Own

12:50-2 p.m.


Funding Opportunities for Physician-Scientists

2-2:30 p.m.


Faculty "Office Hours"

2:30-4 p.m.


Workshop Post-Test

4-4:30 p.m.


Specific Aims Recap and Closing Remarks

4:30-6 p.m.


Closing Dinner and Party

7-10 p.m.


Sunday
, July 29

Departure


^Not eligible for CME credit


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Mark W. Geraci, Indiana University, Indianapolis, IN