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FINDING CURES TOGETHER<sup>SM</sup>

Environmental Carcinogenesis: Potential Pathway to Cancer Prevention

Program 


Saturday, June 22 

Sunday, June 23

Monday, June 24


Saturday, June 22

Welcome and Keynote Address
7-8 p.m.

Welcome and Introduction
Margaret L. Kripke, University of Texas MD Anderson Cancer Center, Houston, Texas

Keynote Address: The global impact of environmental carcinogenesis and interventions for prevention
Christopher P. Wild, Emeritus Director, International Agency for Research on Cancer, Lyon, France

Opening Reception
8-9 p.m.

Top of page


Sunday, June 23

Continental Breakfast
7-8 a.m.

Plenary Session 1: Recent Advances in Cancer Prevention and Early Detection 
Session Chair: Ernest T. Hawk, University of Texas, MD Anderson Cancer Center, Houston, Texas
8-9:45 a.m.

New concepts in precision prevention
Timothy R. Rebbeck, Dana Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts

The microbiome and cancer
Jiyoung Ahn, New York University Langone Medical School, New York, New York

Mutational spectra of environmental carcinogens as biomarkers for early detection of cancer
Bogdan Fedeles, Massachusetts Institute of Technology, Cambridge, Massachusetts

Genomic UV-hypersensitive sites as sentinels for personal UV exposure*
Douglas Brash, Yale School of Medicine, New Haven, Connecticut

Break
9:45-10 a.m.

Plenary Session 2: Integration of Genomics and Epidemiology
Session Chair: Bogdan Fedeles, Massachusetts Institute of Technology, Cambridge, Massachusetts
10 a.m.-12 p.m.

Genetic susceptibility and biologic markers of carcinogen exposure
Jesse J. Salk, University of Washington, Seattle, Washington

Mutational signatures of environmental carcinogens in mouse and human cancers
Allan Balmain, University of California Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Interactions of genetic variants and environmental factors
Ulrike Peters, Fred Hutchinson Cancer Research Center, Seattle, Washington

Lunch (provided)
12-1 p.m.

Plenary Session 3: Environmental Contributors to Human Cancers 
Session Chair: Julia Brody, Silent Spring Institute, Newton, Massachusetts
1-3:15 p.m.

Environmental contributors to childhood cancers
Catherine Metayer, University of California School of Public Health, Berkeley, California

Neighborhood matters:  Residential levels of air toxics and increased risk of early childhood acute lymphocytic leukemia 
Elaine Symanski, University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas

Timing of environmental contributions to cancer in a multi-generational cohort
Barbara A. Cohn, Public Health Institute, Oakland, California

Role of endocrine disruptors in cancer development
Gail S. Prins, University of Illinois College of Medicine, Chicago, Illinois

Glyphosate as a potential carcinogen for multiple myeloma*
Yong Li, Cleveland Clinic, Cleveland, Ohio

Break
3:15-3:30 p.m.

Plenary Session 4: Recent Progress in Identifying and Defining Carcinogens
Session Chair: John D. Groopman, Johns Hopkins School of Public Health, Baltimore, Maryland
3:30-5:45 p.m.

Key characteristics of carcinogens
Martyn T. Smith, University of California, Berkeley, California

High throughput methods for screening for breast carcinogens
Ruthann Rudel, Silent Spring Institute, Newton, Massachusetts

Role of environment in genetic predisposition: Lessons from tobacco studies
Chris I. Amos, Baylor College of Medicine, Houston, Texas

The Halifax Project: Can a chemical mixture be a virtual carcinogen?
William H. Goodson III, California Pacific Medical Center, San Francisco, California

An integrative mouse model of gastric premalignancy that combines early genomic alterations with disease-relevant carcinogenic exposure*
Nilay Sethi, Dana-Farber Cancer Institute, Boston, Massachusetts

5:45-7:45 p.m.

Dinner (on own)
7:45 p.m.

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Monday, June 24

Continental Breakfast
7-8 a.m.

Plenary Session 5: Selected Highly Rated Abstracts
Session Chair: Margaret L. Kripke, University of Texas MD Anderson Cancer Center, Houston, Texas
8-9 a.m.

Exposure-based assessment and economic valuation of adverse birth outcomes and cancer risk due to nitrate in United States drinking water*
Alexis Temkin, Environmental Working Group, Washington, DC

Fine particulate matter and mortality among pediatric, adolescent, and young adults with cancer*
Judy Ou, Huntsman Cancer Institute, Salt Lake City, Utah

North Carolina environmental quality is associated with distant/metastatic breast cancer: Evidence for rural-urban disparities*
Larissa Gearhart-Serna, Duke University, Durham, North Carolina

Latent class analysis of multipollutant exposure*
Terry Hyslop, Duke University, Durham, North Carolina

Keynote Address: Challenges and ppportunities in environmental carcinogenesis: The NIEHS persepctive 
Richard P. Woychik, National Institute of Environmental Health Science/National Toxicology Program, Research Triangle Park, North Carolina
9-10 a.m.

Break
10-10:15 a.m.

Plenary Session 6: Innovative Approaches for Measuring Carcinogen Exposure
Session Chair: Gwen Collman, National Institute of Environmental Health Science, Research Triangle Park, North Carolina
10:15 a.m.-12:00 p.m.

The exposome and cancer
Ted Schettler, Science and Environmental Health Network, Bolinas, California

A compendium of mutational signatures due to environmental exposures
Serena Nik-Zainal, MRC Cancer Unit, University of Cambridge, Cambridge, England

Novel methods for detecting carcinogen exposure
Bevin P. Engelward, Massachusetts Institute of Technology, Boston, Massachusetts

Noninvasive epidermal sampling as a means of genomic UV dosimetry*
Kenneth Tsai, Moffitt Cancer Center, Tampa, Floridia

Lunch (provided)
12-1:15 p.m.

Plenary Session 7: Pathways to Prevention
Session Chair: Timothy R. Rebbeck, Dana Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
1:15-3:15 p.m.

Systems approach to cancer prevention
Polly Hoppin, University of Massachusetts, Lowell, Massachusetts

Impact of workplace exposures on cancer disparities
Paul Demers, Occupational Cancer Research Centre, Toronto, Ontario, Canada

Public engagement
Julia Brody, Silent Spring Institute, Newton, Massachusetts

Applying epidemiology to prevention
John D. Groopman, Johns Hopkins School of Public Health, Baltimore, Maryland

Break
3:15-3:30 p.m.

Plenary Session 8: Pathways to Prevention
Session Chair: Timothy R. Rebbeck, Dana Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
3:30-5 p.m.

A brief orientation to implementation science at the National Cancer Institute
Gila Neta, National Cancer Institute, Bethesda, Maryland

Carcinogens in consumer products: How science can inform policy to benefit public health
Veena Singla, University of California, San Francisco, California

Integrating environmental exposures with cancer control
Debbie Winn, National Cancer Institute, Bethesda, Maryland

Closing Remarks 
Session Chair: Ernie T. Hawk, University of Texas MD Anderson Cancer Center, Houston, Texas

*Short talk from proffered abstract