Program: Monday, February 24
Sunday, Feb. 23
Tuesday, Feb. 25
Wednesday, Feb. 26
monday, february 24
- Major Symposium 1: Personalized Therapies Targeting Neoantigens
- Major Symposia 2-3
- Cancer Immune Evasion
- New Cancer Immunotherapy Biology
- Keynote Session 2
- Spotlight Sessions 1-2
- Endogenous Retroviruses in the Anti-Tumor Immune Response (Dark Genome)
- T Cell Fitness, Dysfunction, and Exhaustion
Monday, February 24
continental breakfast
7-8 a.m.
Major Symposium 1: Personalized Therapies Targeting Neoantigens
8-9:30 a.m.
Session Chair: Alena Gros, VHIO Vall D’Hebron Institute of Oncology, Barcelona, Spain
- 8:05 a.m. | Personalized cancer vaccines: Encouraging results and new opportunities
Catherine Wu, Dana-Farber Cancer Institute, Brookline, Massachusetts - 8:25 a.m. | Immunogenicity and therapeutic targeting of recurrently mutated ‘public’ neoantigens
Christopher A. Klebanoff, Memorial Sloan Kettering Cancer Center, New York, New York - 8:45 a.m.
Alena Gros - 9:05 a.m. | Discussion / Q&A
break
9:30-10 a.m.
Major Symposia 2-3
10-11:30 a.m.
Major Symposium 2: Cancer Immune Evasion
Session Chair: Helen Rizos, Macquarie University, Sydney, Australia
- 10:05 a.m.
Annette Paschen, University Hospital Essen, Essen, Germany - 10:25 a.m.
Speaker to be announced - 10:45 a.m. | Hide and Seek: Immune evasion in melanoma
Helen Rizos - 11:05 a.m. | Discussion / Q&A
Major Symposium 3: New Cancer Immunotherapy Biology
Session Chair: Caroline Robert, Gustave Roussy, Paris, France
- 10:05 a.m.| New developments in drugging the adenosine pathway
Juan C. Jaen, Arcus Biosciences, Burlingame, California - 10:25 a.m. | Decoding and reprogramming T cell circuits with CRISPR
Alexander Marson, University of California, San Francisco, California - 10:45 a.m. | New development in translational control of T cells
Caroline Robert - 11:05 a.m. | Discussion / Q&A
BREAK
11:30 a.m.-12 p.m.
keynote session 2
12-1 p.m.
Session Chair: Ira Mellman, Genentech, Inc., South San Francisco, California
- 12:05 p.m.
James R. Heath, Institute for Systems Biology, Seattle, Washington - 12:35 p.m. | Expanding the cytokine alphabet for immunotherapy
K. Christopher Garcia, Stanford University School of Medicine, Stanford, California
Spotlight on Proffered Papers Session 1
1-1:45 p.m.
Poster Session A / Exhibit Show / Lunch
1:45-4:45 p.m.
spotlight sessions 1 and 2
5-6:20 p.m.
spotlight SESSION 1: Endogenous Retroviruses in the Anti-Tumor Immune Response (Dark Genome)
Session Chair: George Kassiotis, The Francis Crick Institute, London, England
- 5:05 p.m. | Identification and targeting of HERV-E derived tumor-restricted antigens in kidney cancer
Richard W. Childs, National Heart, Lung, and Blood Institute, Bethesda, Maryland - 5:25 p.m.
Sebastian Amigorena, Institut Curie, Paris, France - 5:45 p.m. | Immunogenicity of endogenous retroelements in cancer
George Kassiotis - 6:05 p.m. | Discussion / Q&A
Spotlight Session 2: T Cell Fitness, Dysfunction, and Exhaustion
Session Chair: Andrea Schietinger, Memorial Sloan Kettering Cancer Center, New York, New York
- 5:05 p.m.
Andrea Schietinger - 5:25 p.m.
E. John Wherry, University of Pennsylvania, Philadelphia, Pennsylvania - 5:45 p.m.
Luca Gattinoni, Leibniz Institute for Immunotherapy, Regensburg, Germany - 6:05 p.m. | Discussion / Q&A
evening off
6:20 p.m.