Program
Saturday, November 7, 2020
Sunday, November 8, 2020
- Plenary Session 1: Molecular Stratification
- Plenary Session 2: DNA Repair and Replication
- Plenary Session 3: Functional Genomics and Proteomics
- Plenary Session 4: Novel Model Systems
Monday, November 9, 2020
Saturday, November 7, 2020
Educational Session
4-5:30 p.m.
Douglas A. Levine, NYU Langone Health, New York, New York
Blake Gilks, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada
Victoria Bae-Jump, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Break and Welcome
5:30-6 p.m.
Opening Keynote Session
6-7 p.m.
Recent progress with PTEN
Ramon Parsons, Icahn School of Medicine at Mount Sinai, New York, New York
Poster Session A / Opening Reception
7-8:30 p.m.
Sunday, NOVEMBER 8, 2020
Continental Breakfast
7-8 a.m.
Plenary Session 1: Molecular Stratification
8-10 a.m.
Title to be announced
David Church, Wellcome Centre for Human Genetics, University of Oxford, Oxford, England
Title to be announced
Naveena Singh, Barts Health NHS Trust, London, England
Title to be announced
Jessica N. McAlpine, University of British Columbia, Vancouver, British Columbia, Canada
Short talks from proffered abstracts
Break
10-10:30 a.m.
Plenary Session 2: DNA Repair and Replication
10:30 a.m.-12:30 p.m.
POLE mutations in endometrial cancer: Consequences and mechanisms
Polina V. Shcherbakova, University of Nebraska, Lincoln, Nebraska
Defective DNA mismatch repair: Where to in management of endometrial cancer
Paul Goodfellow, Ohio State University, Columbus, Ohio
Title to be announced
Tjalling Bosse, Leiden University Medical Center, Leiden, Netherlands
Short talks from proffered abstracts
FREE TIME / LUNCH ON OWN
12:30-1:30 P.M.
Plenary Session 3: Functional Genomics and Proteomics
1:30-3:30 p.m.
The mutational landscape of normal human endometrial epithelium
Luiza Moore, Wellcome Trust Sanger Institute, Cambridge, England
Mimatch repair deficiency and survival in stage I endometrial Cancer
Russell R. Broaddus, The University of Texas MD Anderson Cancer Center, Houston, Texas
Proteogenomic characterization of endometrial carcinoma
David Fenyo, NYU Langone Health, New York, New York
Short talks from proffered abstracts
Break
3:30-4 p.m.
Plenary Session 4: Novel Model Systems
4-6 p.m.
Title to be announced
Victoria Bae-Jump, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Title to be announced
Stephen D. Hursting, University of North Carolina Chapel Hill, Chapel Hill, North Carolina
Organoids to model endometrial carcinoma subtypes
David G. Huntsman, British Columbia Cancer Research Center, Vancouver, British Columbia, Canada
Chromatin regulation of the endometrium: What are our models telling us?
Ronald L. Chandler, Michigan State University, East Lansing, Michigan
Poster Session B / Reception
6-7:30 P.M.
MONDAY, NOVEMBER 9, 2020
Continental Breakfast
7-8 a.m.
Plenary Session 5: Immunotherapy
8-10 a.m.
Immunology of endometrial cancers: tumor genetics, immune recognition, and immunotherapy response
Dmitriy Zamarin, Memorial Sloan Kettering Cancer Center, New York, New York
Coordinated T and B cell responses exert immune pressure against malignant progression
Jose R. Conejo-Garcia, Moffitt Cancer Center, Tampa, Florida
Title to be announced
Alexandra Snyder, Merck Oncology, Rahway, New Jersey
Short talks from proffered abstracts
Break
10-10:30 a.m.
Plenary Session 6: Targeted Therapeutics
10:30 a.m.-12:30 p.m.
DNA Damaging Agents in Endometrial Cancer
Shannon Neville Westin, The University of Texas MD Anderson Cancer Center, Houston, Texas
Title to be announced
Helen J. MacKay, Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Novel antibody-drug conjugates (ADC) for the targeted treatment of endometrial cancer
Alessandro D. Santin, Yale University, New Haven, Connecticut
Title to be announced
Remi A. Nout, Leiden University Medical Center, Leiden, Netherlands