In This Section

Program

All presentations are scheduled to be live, in-person presentations at the date and time specified below unless noted otherwise.  Program is subject to change.
[R] – remote presentation

FRIDAY, JANUARY 7, 2022

Registration
4-8 p.m.


Welcome and Opening KeynotE Lecture
6-7:30 p.m.

Welcome and Introduction of Keynote Speaker
Dafna Bar-Sagi, New York University Langone Medical Center, New York, New York

Keynote Lecture
Mariano Barbacid, Spanish National Cancer Center (CNIO), Madrid, Spain

Introduction of Rising Star Speaker
Deborah K. Morrison, National Cancer Institute, Frederick, Maryland

Rising Star Lecture
Andrew Aguirre, Harvard Medical School, Boston, Massachusetts

Opening Reception
7:30-9:30 p.m.

Saturday, JANUARY 8, 2022

Continental Breakfast
7-8 a.m.

Plenary Session 1: Structure/function/biochemistry
8-10:15 a.m.
Session Chair: Frank McCormick, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Title to be announced
Dhirendra K. Simanshu, Frederick National Laboratory for Cancer Research, Frederick, Maryland

Additional speakers to be announced

Two short-talks from proffered papers


Break
10:15-10:35 a.m.

Plenary Session 2: Signaling Networks
Session Chair: Deborah K. Morrison, National Cancer Institute, Frederick, Maryland
10:35 A.M.-12:50 P.M.

Title to be announced
Channing J. Der, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Title to be announced
Shiva Malek, Genentech, Inc., South San Francisco, California

Title to be announced
William C. Hahn, Dana-Farber Cancer Institute, Boston, Massachusetts

Two short-talks from proffered papers


Lunch on own/Free time
12:50-2:15 p.m.

Plenary Session 3: Site-specific session
Session Chair: Christin E. Burd, The Ohio State University, Columbus, Ohio
2:15-4:30 p.m.

Title to be announced
Christin E. Burd

K-RAS hyperexchange mutants in colorectal cancer
Kevin M. Haigis, Dana-Farber Cancer Institute, Boston, Massachusetts

Title to be announced
Lukas E. Dow, Weill Cornell Medicine, New York, New York

Two short-talks from proffered papers


Poster Session A/Reception
4:45-7 p.m.

Evening Off/Dinner on Own
7 p.m.

Sunday, January 9, 2022

Continental Breakfast
7-8 a.m.
Plenary Session 4: Metabolism
Session Chair: Dafna Bar-Sagi, New York University Langone Medical Center, New York, New York
8-10:15 a.m.

Title to be announced
Dafna Bar-Sagi

Additional speakers to be announced

Two short-talks from proffered papers

Break
10:15-10:35 a.m.

Plenary Session 5: RASopathies/RAS Superfamily
Session Chair: Marco Tartaglia, Ospedale Pediatrico Bambino Gesù, Rome, Italy
10:35 a.m.-12:50 p.m.

Title to be announced
Marco Tartaglia

Title to be announced
Christian P. Kratz, Hannover Medical School, Hannover, Germany [R]

Title to be announced
Anne Goriely, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

Two short-talks from proffered papers

Free time/Lunch on own
12:50-2:15 p.m.
Plenary Session 6: Immunotherapy/Immunity
Session Chair: Julian Downward, The Francis Crick Institute, London, England
2:15-4:30 p.m.

Title to be announced
Marina Pasca di Magliano, University of Michigan Medical School, Ann Arbor, Michigan

Impact of Ras inhibition on tumor immune evasion
Julian Downward

Speaker to be announced

Two short-talks from proffered papers

Poster Session B/Reception
4:45-7 p.m.

Evening Off/Dinner on Own
7 p.m.


Monday, January 10, 2022

Continental Breakfast
7-8 a.m.
Closing Keynote Lecture
8-8:45 a.m.

Introduction of Keynote Speaker
Mariano Barbacid, Spanish National Cancer Center (CNIO), Madrid, Spain

Keynote Lecture
Karen M. Cichowski, Brigham and Women’s Hospital, Boston, Massachusetts


Plenary Session 7: Targeting RAS
8:50-10:35 a.m.

Title to be announced
Kirsten L. Bryant, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Additional speakers to be announced


BREAK
10:35-10:55 A.M.

Plenary Session 8: Resistance Mechanisms and Emerging Clinical Data
Session Chair: Mariano Barbacid, Spanish National Cancer Center (CNIO), Madrid, Spain
10:55 A.M.-12:55 P.M.

Unconventional approaches to drugging the MAPK pathway
Rene Bernards, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Additional speakers to be announced

Short-talk from proffered papers


Closing Remarks and Departure
12:55-1 p.m.

Dafna Bar-Sagi, New York University Langone Medical Center, New York, New York