Malcolm A.S. Moore, DPhil, an emeritus member of the Cell Biology Program in the Sloan Kettering Institute in New York, and a member of the AACR since 1981, died September 23, 2025. He was 81 years old.
Moore’s research focused on the factors controlling the differentiation of hematopoietic progenitor cells into mature cells. In 1984, he and Karl Welte, a member of his lab, isolated granulocyte colony-stimulating factor (G-CSF), a protein that stimulates the growth of new blood cells. This later became a basis for filgrastim, a drug used to treat neutropenia.
Born in the United Kingdom in 1944, Moore received a doctorate from the University of Oxford in 1967. He was a visiting fellow at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, from 1967 to 1969 and senior research scientist and head of the Laboratory of Developmental Biology from 1970 to 1974. He then moved to Memorial Sloan Kattering Cancer Center as the Edid A. Haupt chair of cell biology.
He received the William B. Coley Award for Basic and Tumor Immunology from the Cancer Research Institute in 1995, the Hope Funds Award of Excellence in Basic Research in 2008, a Lifetime Achievement Award from the Cancer Research and Treatment Fund in 2011, and the C. Chester Stock Award Lectureship from MSK in 2013.
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A brilliant and talented scientist and mentor. His legacy lives on in the many clinicians, scientists and researchers he mentored as well as in the patients who benefited from his discoveries. He was dear friend who will be missed
Malcolm was a wonderful father to Julian (Sue) and Andy (Melissa), a wonderful grandad to Stephen, Samantha, Alexander and Chloe, and a great husband. We are all heartbroken. He was a brilliant scientist and the consummate British gentleman. He will be missed.
Dear Fran, we are all so saddened by Malcolm's passing. He was a wonderful, kind man loved by all our family, and he made this world a better place with his amazing contributions to medical science. There are many families who will be forever grateful for his expertise and kindness show to patients whom he treated in his long, distinguished career. We treasure our memories of time spent with you both in Scotland and in New York, and he will live on in our hearts forever. Our thoughts and prayers are with you Fran, Malcolm was a gentleman with a heart of gold and will be sorely missed by us all xxx
A brilliant man, who was kind and patient. He was devoted to his family, which despite his scientific achievements, is the most important thing.