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Confirmed Plenary Sessions are listed below. Additional sessions will be posted in mid-September.

Plenary Sessions

Saturday, April 15, 2023
Beating Kras: A 30-Year Overnight Sensation
Chair: Dafna Bar-Sagi, NYU Langone Health, New York, New York

  • Dafna Bar-Sagi, NYU Langone Health, New York, New York
  • Pasi A. Jänne, Dana-Farber Cancer Institute, Boston, Massachusetts
  • Beatriz M. Carreno, University of Pennsylvania, Philadelphia, Pennsylvania
  • Frank McCormick, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Sunday, April 16, 2023
Opening Plenary Session: Advancing the Frontiers of Cancer Science and Medicine
Chair: Robert H. Vonderheide,
Penn Medicine Abramson Cancer Center, Philadelphia, Pennsylvania

  • Deborah Schrag, Memorial Sloan Kettering Cancer Center, New York, New York
  • David G. Denardo, Washington University School of Medicine in St. Louis, St. Louis, Missouri
  • Tomi Akinyemiju, Duke University School of Medicine, Durham, North Carolina
  • Robert Yarchoan, National Cancer Institute, Bethesda, Maryland
  • Teresa A. Zimmers, Indiana University School of Medicine, Indianapolis, Indiana

Monday, April 17, 2023
Early Detection and Interception of Cancer
Chair: Peter Kuhn,
University of Southern California, Los Angeles, California

  • Phil H. Jones, Wellcome Sanger Institute, Cambridge, United Kingdom
  • Eun-Sil Shelley Hwang, Duke Cancer Institute, Durham, North Carolina
  • Phillip G. Febbo, Illumina Inc., San Diego, California
  • Elana J. Fertig, Johns Hopkins University, Baltimore, Maryland
  • Karriem S. Watson, National Institutes of Health, Bethesda, Maryland

Tuesday, April 18, 2023
Embracing Immune Ecosystems
Chair: Judith A. Varner,
UCSD Moores Cancer Center, La Jolla, California

  • Florent Ginhoux, Agency for Science, Technology and Research (A*STAR), Singapore
  • Miriam Merad, Icahn School of Medicine at Mount Sinai, New York, New York
  • Jose R. Conejo-Garcia, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida
  • Gianpietro Dotti, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • Dario A. Vignali, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Wednesday, April 19, 2023
New Concepts in Drug Discovery and Engineering
Chair: Sanjay V. Malhotra,
Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon

  • Jennifer R. Cochran, Stanford University, Stanford, California
  • Andrea L. Kasinski, Purdue University, West Lafayette, Indiana
  • Gregory R. Bowman, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  • Evan A. Scott, Northwestern University, Evanston, Illinois
  • Puja Sapra, AstraZeneca – MedImmune, LLC, Gaithersburg, Maryland

AACR Annual Meeting 2023 Highlights: Vision for the Future
Chair: Robert H. Vonderheide, Penn Medicine Abramson Cancer Center, Philadelphia, Pennsylvania

  • Speakers to be announced

Major Symposia

  • 25th Anniversary of Trastuzumab: Impact and Future Directions
  • Addressing the Global Oncology Disease Burden
  • Advances in Quantitative Sciences in Cancer: From Atomic Scale to Patients
  • Advances in Supportive Care
  • Artificial Intelligence at the Interface of Sparse Clinical Data and Big Laboratory Data
  • Biological Basis of Novel Targets for Solid Tumors
  • The Biology of Obesity, Aging, and Nutrition
  • Cancer Ecosystem and the Microenvironment
  • Cancer Stem Cells and Immuno-oncology
  • CAR T Cells in Solid Tumors
  • Cellular Therapies for Cancer
  • Clinical Opportunities and Challenges with Liquid Biopsies
  • Clinical Strategies for Myeloid Cell Modulation in Cancer
  • Complicity of Benign Cells in the Tumor Microenvironment
  • The Connection between Autoimmunity and Immunotherapy in Cancer
  • DNA Damage and Therapeutic Strategies
  • Electronic Health Records and Cancer Learning Health Systems
  • Future of Phase I Clinical Trials
  • Histone Alterations and Epigenetics as Cancer Drivers
  • Humoral Immune Response and Tertiary Lymphoid Structures in Cancer
  • Immunometabolism in the Tumor Microenvironment
  • Impact of Clonal Hematopoiesis in Cancer
  • Innate Lymphocytes and Cancer
  • Metabolic Influence on the Cancer Cell State
  • Microbiome and Cancer Immunotherapy
  • Molecular Mechanisms of KRAS Pathway Inhibitors
  • Myeloid Cells and Biological Responses in Cancer
  • New Horizons for T Cell Immunity and Checkpoints
  • New Insights into Cancer Initiation, Progression, and Therapy through Big Data Resources
  • Organ-Specific Regulation of Metastasis
  • Overcoming Drug Resistance
  • Pathogenesis of Childhood Cancers
  • Presidential Select Symposium: Pregnancy and Cancer
  • Radiation Therapy, DNA Damage, and Immune Response
  • RNA and the Cancer Transcriptome
  • Role of Aging in Cancer
  • Sex Hormones and Cancer
  • Spatial Technologies for Mapping Cancer Cell Architecture
  • Stress, Stemness, and Drug Resistance
  • Systemic Effects of Cancer
  • T Cells and the Tumor
  • Tumor Glycome in Metastasis, Immune Suppression, and Drug Resistance

Advances in Diagnostics and Therapeutics

  • Advances in FLASH Radiation
  • Cancer Vaccines: Back to the Future
  • Early Detection of Cancer and the Science of Early Cancer
  • Functional Precision Medicine
  • Immune Profiling and Immune Health in Cancer
  • Multiomics in Diagnosis and Care Management
  • New Approaches to Early Detection
  • Novel Computational Tools to Probe Cancer at the Single Cell Level
  • Novel Drug Design and Engineering
  • Surgical Advances with Chemical Probes and Intraoperative Imaging

Advances in Organ Site Research

  • Advances in Breast Cancer
  • Advances in Brain Tumors
  • Advances in Gastrointestinal Malignancies
  • Advances in Leukemia Research and Treatment
  • Advances in Lymphoma
  • Advances in Melanoma Research and Treatment
  • Advances in Non–Small Cell Lung Cancer
  • Advances in Ovarian Cancer
  • Advances in Pancreas Cancer
  • Advances in Prostate Cancer
  • Advances in Sarcoma Biology
  • Advances in Small Cell Lung Cancer and Neuroendocrine Cancer

Advances in Population Sciences

  • Behavioral Economics and Psychology to Improve Cancer Care
  • Cancer and COVID-19 Vaccination
  • Population Sciences in the Era of Omics

Advances in Prevention Research

  • Advances in Cancer Screening and Prevention
  • Germline Genetics and Cancer Predisposition
  • The Science Driving Novel Treatment of Nicotine Addiction
  • Strategies for Cancer Interception

Advances in the Science of Cancer Disparities

  • Achieving Equitable Access to Cancer Care
  • Disparities and Cancer Outcomes
  • The Biology Driving Cancer Disparities


  • CAR Cells: Which CAR to Drive?
  • Has Adding Anti-PD1/PDL1 to Other Treatments Lived Up to the Hope?
  • How Can We Improve Data-Sharing?
  • How Can We Improve Workforce Recruitment and Retention?
  • How Can We Make Cancer Care at Home the Norm and Not the Exception?
  • What Are the Challenges and Solutions in Adolescent and Young Adult Cancers?
  • What Does a Biostatistician Really Think of Your Study and Why?
  • What Is the Best Way to Engage Diverse Communities in Cancer Research?
  • What is the Future of Antiangiogenesis?
  • What Is the Utility of PDX and Organoid Models in the Era of Immuno-oncology?